Nicotinamide Mononucleotide (NMN)
NMN is the revolutionary new molecule used by Harvard Scientists to slow and even reverse the signs of ageing. Studies have shown NMN supplements activate anti-ageing pathways and restore genes back in to their youthful configuration, boosting energy metabolism, promoting healthy brain and cardiovascular function, repairing aged DNA and activating Sirtuins associated with longevity.
• NMN is more effective than other metabolites at restoring NAD+ levels inside of cells.
• NAD+ is found in every cell you have and is essential to cellular metabolism, the chemistry that keeps you up and running.
NAD+ increases ATP production – the energy currency of your cells. NAD+ levels control the activity of DNA repair and the seven enzymes that guard against aging called, “sirtuins.”
These proteins are nicknamed “guardians of the genome” because they play a key role in maintaining cellular health, controlling inflammation and switching off genes that are associated with aging. Sirtuins maintain telomere length – the end caps of DNA that keep chromosomes from unraveling and can only function in the presence of NAD+.
Introducing EliX Health NMN
One product to support the long-term health of your cells.
Elix Health NMN is a daily supplement that is designed to increase cellular NAD+ levels and activate sirtuins (a family of genes that play a role in regulating cellular health, and can only function in the presence of NAD+).
NAD+ levels decline naturally as we age. NAD+ is required for vital cellular processes including cellular energy production and healthy DNA maintenance.
NMN is most effective at restoring intracellular NAD+
NAD+ creation and usage in humans
NAD+ can be synthesized in humans from several different molecules (precursors), thru the De Novo and Salvage Pathways.
In the salvage pathway, Nicotinamide (NAM) and Nicotinamide Riboside (NR) are first converted to NMN, which is then further converted to NAD+.
NMN is more correctly referred to as a NAD+ intermediate because NMN is the last step before conversion to NAD+.
Nampt is the rate-limiting step in the salvage process . As we age, Nampt enzyme activity is lower, resulting in less NAM recycling, less NAD+, more disease and aging.
The NAD+ molecule itself is too large to make it through the digestive system intact when taken as capsules, which is why NR and NMN have been used as supplements to increase NAD+ levels in the body.
HUMAN NAD+ METABOLISM
NAD+ can be synthesized in humans from several different molecules (precursors), thru the De Novo and Salvage Pathways.
In the salvage pathway, Nicotinamide (NAM) and Nicotinamide Riboside (NR) are first converted to NMN, which is then further converted to NAD+.
NMN is more correctly referred to as a NAD+ intermediate because NMN is the last step before conversion to NAD+.
Nampt is the rate-limiting step in the salvage process . As we age, Nampt enzyme activity is lower, resulting in less NAM recycling, less NAD+, more disease and aging.
The NAD+ molecule itself is too large to make it through the digestive system intact when taken as capsules, which is why NR and NMN have been used as supplements to increase NAD+ levels in the body.
HUMAN NAD+ METABOLISM
